FSHR agonist 21f

Chemical Structure : FSHR agonist 21f

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货号: PC-20751Not For Human Use, Lab Use Only.

FSHR agonist 21f is a small molecule allosteric agonist of follicle stimulating hormone receptor (FSHR) with high affinity and activation efficacy (pEC50=7.72).

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生物&药学活性

FSHR agonist 21f is a small molecule allosteric agonist of follicle stimulating hormone receptor (FSHR) with high affinity and activation efficacy (pEC50=7.72).
FSHR agonist 21f can activate FSHR, LHCGR and TSHR with high potency and efficacy, while the activation potency for FSHR is more than 10-fold higher than LHCGR and TSHR.

物理化学性质&存储条件

分子量	467.63
分子式	C26H33N3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(C1=NC(C2=CC=CS2)=C3N1CCC4=C3C=C(OC(C)C)C(OC)=C4)N(C(C)(C)C)CC

参考文献

1. Duan J, et al. Nat Commun. 2023 Jan 31;14(1):519.

2. Patent WO2010136438A1

FSHR agonist 21f

生物&药学活性

物理化学性质&存储条件

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FSHR agonist 21f

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物理化学性质&存储条件

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