FPS-ZM1 | RAGE inhibitor | Probechem Biochemicals

Chemical Structure : FPS-ZM1

CAS No.: 945714-67-0

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FPS-ZM1 (RAGE inhibitor)

货号: PC-45627Not For Human Use, Lab Use Only.

FPS-ZM1 is a high-affinity RAGE-specific inhibitor with Ki of 25 nM, blocks Aβ binding to the V domain of RAGE and inhibits Aβ40- and Aβ42-induced cellular stress in RAGE-expressing cells in vitro and in the mouse brain in vivo.

规格	价格	库存
10 mg	￥780	In stock
25 mg	￥1180	In stock
50 mg	￥1980	In stock
100 mg	￥2980	In stock
250 mg		Get quote

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生物&药学活性

FPS-ZM1 is a high-affinity RAGE-specific inhibitor with Ki of 25 nM, blocks Aβ binding to the V domain of RAGE and inhibits Aβ40- and Aβ42-induced cellular stress in RAGE-expressing cells in vitro and in the mouse brain in vivo.

物理化学性质&存储条件

分子量	327.8478
分子式	C20H22ClNO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, 4-chloro-N-cyclohexyl-N-(phenylmethyl)-

参考文献

1. Deane R, et al. J Clin Invest. 2012 Apr;122(4):1377-92.

2. Hong Y, et al. Neurochem Res. 2016 May;41(5):1192-9.

3. Kwak T, et al. Oncogene. 2017 Mar;36(11):1559-1572.

FPS-ZM1 (RAGE inhibitor)

生物&药学活性

物理化学性质&存储条件

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FPS-ZM1 (RAGE inhibitor)

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物理化学性质&存储条件

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