FPR2 agonist compound 8

Chemical Structure : FPR2 agonist compound 8

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货号: PC-24177Not For Human Use, Lab Use Only.

FPR2 agonist compound 8 is a potent, selective agonist of formyl peptide receptor 2 (FPR2/ALX, Lipoxin A4 Receptor) with β-arrestin recruitment EC50 of 20 nM, calcium mobilization EC50 of 740 nM.

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生物&药学活性

FPR2 agonist compound 8 is a potent, selective agonist of formyl peptide receptor 2 (FPR2/ALX, Lipoxin A4 Receptor) with β-arrestin recruitment EC50 of 20 nM, calcium mobilization EC50 of 740 nM.

物理化学性质&存储条件

分子量	417.31
分子式	C19H21BrN4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-(4-bromophenyl)ureido)-2-cyclopentyl-N-(pyridin-3-yl)acetamide

参考文献

1. Maciuszek M, et al. Eur J Med Chem. 2021 Mar 15;214:113194.