FPR1 agonist fMLF | FPR1 agonist | Probechem Biochemicals

Chemical Structure : FPR1 agonist fMLF

CAS No.: 59880-97-6

加入收藏

FPR1 agonist fMLF (N-formyl-Met-Leu-Phe, NSC 350593)

货号: PC-72083Not For Human Use, Lab Use Only.

FPR1 agonist fMLF (NSC 350593) is a potent, selective formylpeptide receptor-1 (FPR1) agonist with EC50 of 80 nM in calcium flux, Ki of 38 nM.

规格	价格	库存
10 mg	￥780	In stock
50 mg	￥1780	In stock
100 mg	￥2980	In stock
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

FPR1 agonist fMLF (NSC 350593) is a potent, selective formylpeptide receptor-1 (FPR1) agonist with EC50 of 80 nM in calcium flux, Ki of 38 nM.
fMLF activates mononuclear phagocytes to cellular activation, which is characterized by cellular polarization, chemotaxis, and release of proteolytic enzymes.
fMLF induces contractions in isolated guinea pig jejunum (EC50 = 11 nM), proximal colon (EC50 = 3.5 nM), and distal colon (EC50 = 2.2 nM).
fMLF induces neurotransmitter release from enteric motor neurons in vitro.

物理化学性质&存储条件

分子量	437.6
分子式	C21H31N3O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-formyl-L-methionyl-L-leucyl-L-phenylalanine

参考文献

1. Lind S, et al. J Leukoc Biol. 2021 Jun;109(6):1105-1120.

2. Hu Y, et al. Chembiochem. 2014 Nov 3;15(16):2420-6.

3. Partida-Sánchez S, et al. J Immunol. 2004 Feb 1;172(3):1896-906.

4. Salamah MF, et al. J Thromb Haemost. 2019 Jul;17(7):1120-1133.

FPR1 agonist fMLF (N-formyl-Met-Leu-Phe, NSC 350593)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

FPR1 agonist fMLF (N-formyl-Met-Leu-Phe, NSC 350593)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.