FPPS-IN-11

Chemical Structure : FPPS-IN-11

CAS No.: 1250273-31-4

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货号: PC-38605Not For Human Use, Lab Use Only.

FPPS-IN-11 is a potent, allosteric, non-bisphosphonate farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 200 nM.

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5 mg	￥1980	In stock
10 mg	￥2980	In stock
25 mg	￥4980	In stock
100 mg		Get quote

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生物&药学活性

FPPS-IN-11 is a potent, allosteric, non-bisphosphonate farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 200 nM.
FPPS-IN-11 displayed similar potencies in biochemical assays to the most potent bisphosphonate, zoledronic acid (IC50=130 nM), and similar to or higher than those of all other bisphosphonates used clinically, such as risedronate, ibandronate, alendronate and pamidronate (IC50 = 150 nM, 340 nM, 850 nM, 950 nM, respectively).

物理化学性质&存储条件

分子量	269.256
分子式	C15H11NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(Carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid

参考文献

1. Wolfgang Jahnke, et al. Nat Chem Biol. 2010 Sep;6(9):660-6.

FPPS-IN-11

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物理化学性质&存储条件

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FPPS-IN-11

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物理化学性质&存储条件

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