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首页-新冠病毒相关-SARS-CoV-2 Inhibitors-FOY-251
FOY-251

Chemical Structure : FOY-251

CAS No.: 71079-09-9

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FOY-251 (FOY251)

货号: PC-49155Not For Human Use, Lab Use Only.

FOY-251 is a camostat metabolite and inhibitor of TMPRSS2 protease activity with IC50 of 33.3 nM, completely suppresses TMPRSS2 activity at 1 uM, inhibit SARS-2-S-driven cell entry with comparable efficiency (EC50=178 nM) with camostat mesylate.

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5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3280 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

FOY-251 is a camostat metabolite and inhibitor of TMPRSS2 protease activity with IC50 of 33.3 nM, completely suppresses TMPRSS2 activity at 1 uM, inhibit SARS-2-S-driven cell entry with comparable efficiency (EC50=178 nM) with camostat mesylate.

物理化学性质&存储条件

分子量 409.413
分子式 C17H19N3O7S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(4-((4-guanidinobenzoyl)oxy)phenyl)acetic acid compound with methanesulfonic acid (1:1)

参考文献

1. Shrimp JH, et al. bioRxiv. 2020 Aug 6:2020.06.23.167544.

2. Hoffmann M, et al. EBioMedicine. 2021 Mar;65:103255.

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