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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-FOB02-04A
FOB02-04A

Chemical Structure : FOB02-04A

CAS No.: 2363169-04-2

FOB02-04A

货号: PC-23118Not For Human Use, Lab Use Only.

FOB02-04A is a selective, bitopic and full agonist of dopamine 3 receptor (D3R) with Ki of 1.85 nM, 47- and 155-fold selective over D2R and D4R.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

FOB02-04A is a selective, bitopic and full agonist of dopamine 3 receptor (D3R) with Ki of 1.85 nM, 47- and 155-fold selective over D2R and D4R.

物理化学性质&存储条件

分子量 433.56
分子式 C25H31N5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-((1R,2S)-2-(((2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholino)methyl)cyclopropyl)ethyl)-1H-indole-2-carboxamide

参考文献

1. Arroyo-Urea S, et al. Nat Commun. 2024 Sep 5;15(1):7759.

2. Battiti FO, et al. ACS Med Chem Lett. 2020 Feb 28;11(10):1956-1964.

3. Battiti FO, et al. J Med Chem. 2019, 62 (13), 6287–6314.

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