FOB02-04 | D3R agonist | Probechem Biochemicals

Chemical Structure : FOB02-04

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FOB02-04 (FOB 02-04)

货号: PC-22633Not For Human Use, Lab Use Only.

FOB02-04 is a potent, selective dopamine D3 receptor (D3R) agonist with Ki of 2.84 nM, weak affinity with Ki of 106 nM for D2R.

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生物&药学活性

FOB02-04 is a potent, selective dopamine D3 receptor (D3R) agonist with Ki of 2.84 nM, weak affinity with Ki of 106 nM for D2R.
FOB02-04 significantly reduced impulsive choices in high-impulsive rats but had no effects in low-impulsive rats.

物理化学性质&存储条件

分子量	433.56
分子式	C25H31N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	trans-N-(2-(2-(((2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholino)methyl)cyclopropyl)ethyl)-1H-indole-2-carboxamide

参考文献

1. Battiti FO, et al. J Med Chem. 2019 Jul 11;62(13):6287-6314.

FOB02-04 (FOB 02-04)

生物&药学活性

物理化学性质&存储条件

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FOB02-04 (FOB 02-04)

生物&药学活性

物理化学性质&存储条件

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