FN1-8 | Gli-TAF9 inhibitor | Probechem Biochemicals

Chemical Structure : FN1-8

加入收藏

FN1-8 (Gli inhibitor FN1-8)

货号: PC-61329Not For Human Use, Lab Use Only.

FN1-8 (Gli inhibitor FN1-8) is a synthetic small molecule that efficiently interferes with Gli/TAF9 interaction and downregulate Gli/TAF9-dependent transcriptional activity (at 15 uM).

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

FN1-8 (Gli inhibitor FN1-8) is a synthetic small molecule that efficiently interferes with Gli/TAF9 interaction and downregulate Gli/TAF9-dependent transcriptional activity (at 15 uM).
FN1-8 inhibits non-canonical Gli activation and acts downstream of the canonical Hh pathway.
FN1-8 suppresses cancer cell proliferation in vitro and inhibits tumor growth in vivo.

物理化学性质&存储条件

分子量	447.538
分子式	C29H25N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-hydroxybenzyl)-1,3,5-triphenyl-4,5-dihydro-1H-pyrazole-4-carboxamide

参考文献

1. Bosco-Clément G, et al. Oncogene. 2014 Apr 17;33(16):2087-97.

2. He B, et al. US Patent No. 7714014. 2010

FN1-8 (Gli inhibitor FN1-8)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

FN1-8 (Gli inhibitor FN1-8)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.