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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-FN075
FN075

Chemical Structure : FN075

CAS No.: 864405-82-3

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FN075 (FN 075)

货号: PC-62185Not For Human Use, Lab Use Only.

FN075 is a small-molecule inhibitor targeting Escherichia coli amyloid biogenesis and biofilm formation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    FN075 is a small-molecule inhibitor targeting Escherichia coli amyloid biogenesis and biofilm formation; stimulates α-synuclein amyloid fiber formation.
    FN075 significantly attenuates virulence in a mouse model of urinary tract infection.

    物理化学性质&存储条件

    分子量 481.489
    分子式 C26H18F3NO3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (R)-7-(naphthalen-1-ylmethyl)-5-oxo-8-(3-(trifluoromethyl)phenyl)-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3-carboxylic acid

    参考文献

    1. Cegelski L, et al. Nat Chem Biol. 2009 Dec;5(12):913-9.

    2. Clark MA, et al. Nat Chem Biol. 2009 Sep;5(9):647-54.

    3. Nors Perdersen M, et al. Sci Rep. 2015 May 28;5:10422.

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