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FH1

Chemical Structure : FH1

CAS No.: 2719-05-3

FH1 (NSC12407, BRD-K4477)

货号: PC-42996Not For Human Use, Lab Use Only.

FH1 (BRDK4477) is a small molecule that increase function and proliferation of primary human hepatocytes, promotes the differentiation of iPS-derived hepatocytes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

FH1 (BRDK4477) is a small molecule that increase function and proliferation of primary human hepatocytes, promotes the differentiation of iPS-derived hepatocytes.
FH1 (BRDK4477)  increases the CYP3A4 and CYP2A6 activity
FH1 (BRDK4477)  also increases ~4-fold expression levels of ABC transporter ABCB11 in hepatocytes.

物理化学性质&存储条件

分子量 282.337
分子式 C17H18N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 13 mg/mL

Chemical Name/SMILES

Acetamide, N,N'-(methylenedi-4,1-phenylene)bis-

参考文献

1. Shan J, et al. Nat Chem Biol. 2013 Aug;9(8):514-20.

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