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首页-小分子抑制剂&激动剂-Tyrosine Kinase-FGFR-FGFR4-IN-1
FGFR4-IN-1

Chemical Structure : FGFR4-IN-1

CAS No.: 1708971-72-5

FGFR4-IN-1

货号: PC-42217Not For Human Use, Lab Use Only.

A potent, selective inhibiotr of FGFR4 with IC50 of 0.7 nM, significantly inhibits the proliferation of HuH-7 cells with IC50 of 7.8 nM..

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5 mg ¥2800 In stock
10 mg ¥4000 In stock
50 mg ¥12000 In stock
100 mg ¥16800 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A potent, selective inhibiotr of FGFR4 with IC50 of 0.7 nM, significantly inhibits the proliferation of HuH-7 cells with IC50 of 7.8 nM.

物理化学性质&存储条件

分子量 493.5151
分子式 C24H27N7O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 6.4 mg/mL (Need warming)

Chemical Name/SMILES

1,8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(3-oxo-4-morpholinyl)methyl]-

参考文献

1. Ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors. WO 2015059668 A1

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