FGFR2 inhibitor 38

Chemical Structure : FGFR2 inhibitor 38

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货号: PC-72306Not For Human Use, Lab Use Only.

FGFR2 inhibitor 38 is a potent, selective FGFR2 inhibitor with IC50 of 29 nM, exhibits moderate selectivity for FGFR2 over FGFR1/3 (>13.4 fold).

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

FGFR2 inhibitor 38 is a potent, selective FGFR2 inhibitor with IC50 of 29 nM, exhibits moderate selectivity for FGFR2 over FGFR1/3 (>13.4 fold).
FGFR2 inhibitor 38 exhibited modest potency against SUM52 cell with an IC50 value of 700 nM.

物理化学性质&存储条件

分子量	370.456
分子式	C23H22N4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3-(4-(piperazin-1-yl)phenyl)-1H-indazol-6-yl)phenol

参考文献

1. Lewis D Turner, et al. J Med Chem. 2022 Jan 27;65(2):1481-1504.