FFN246 | Fluorescent SERT, VMAT2 | Probechem Biochemicals

Chemical Structure : FFN246

CAS No.: 2210244-83-8 (free base)

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FFN246 (FFN-246)

货号: PC-38583Not For Human Use, Lab Use Only.

FFN246 is a fluorescent, dual substrate of both SERT and VMAT2 with excitation and emission spectra 392/427 nm, demonstrates the applicability for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation.

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10 mg	￥1580	In stock
25 mg	￥2580	In stock
50 mg	￥4280	In stock
100 mg		Get quote

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生物&药学活性

FFN246 is a fluorescent, dual substrate of both SERT and VMAT2 with excitation and emission spectra 392/427 nm, demonstrates the applicability for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation.
FFN246 could be used for direct examination of SERT activity and SERT inhibitors in 96-well cell culture assays, as well as specific labeling of serotonergic neurons of the dorsal raphe nucleus in the living tissue of acute mouse brain slices.
FFN246 effectively traces serotonin uptake and packaging in the soma of serotonergic neurons.

物理化学性质&存储条件

分子量	292.738
分子式	C15H14ClFN2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	7-(2-Aminoethyl)-1-fluoroacridin-9(10H)-one Hydrochloride

参考文献

1. Adam Henke, et al. ACS Chem Neurosci. 2018 May 16;9(5):925-934.

FFN246 (FFN-246)

生物&药学活性

物理化学性质&存储条件

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FFN246 (FFN-246)

生物&药学活性

物理化学性质&存储条件

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