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首页-小分子抑制剂&激动剂-Others-Other Targets-FEN1-IN-4
FEN1-IN-4

Chemical Structure : FEN1-IN-4

CAS No.: 1995893-58-7

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FEN1-IN-4

货号: PC-21871Not For Human Use, Lab Use Only.

FEN1-IN-4 is a specific, competitive inhibitor of human flap endonuclease-1 (hFEN1) with IC50 of 30 nM, binds to atalytic metals and blocks DNA unpairing.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

FEN1-IN-4 is a specific, competitive inhibitor of human flap endonuclease-1 (hFEN1) with IC50 of 30 nM, binds to atalytic metals and blocks DNA unpairing.

物理化学性质&存储条件

分子量 232.24
分子式 C12H12N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(Cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,3H)-dione

参考文献

1. Jack C Exell, et al. Nat Chem Biol. 2016 Oct;12(10):815-21.

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