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FD-44

Chemical Structure : FD-44

CAS No.: 68207-21-6

FD-44 (FD44;NCS-1-Ric8a inhibitor FD44)

货号: PC-70286Not For Human Use, Lab Use Only.

FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model.

规格 价格 库存 数量
25 mg Get quote
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1 g Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model.

    物理化学性质&存储条件

    分子量 339.457
    分子式 C19H21N3OS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(10H-phenothiazin-10-yl)-2-(piperidin-1-yl)acetamide

    参考文献

    1. Mansilla A, et al. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E999-E1008.

    2. Roca C, et al. J Med Chem. 2018 Jul 17. doi: 10.1021/acs.jmedchem.8b00088.

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