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FCCP

Chemical Structure : FCCP

CAS No.: 370-86-5

FCCP (Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone)

货号: PC-22179Not For Human Use, Lab Use Only.

FCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer.

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25 mg ¥1280 In stock
50 mg ¥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

FCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer.

物理化学性质&存储条件

分子量 254.17
分子式 C10H5F3N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Carbonyl cyanide 4-(trifluoromethoxy) phenyl-hydrazone

参考文献

1. Connop BP et al. J Neurochem. 1999 Apr;72(4):1457-65. 

2. Tanpradit N, et al. J Assist Reprod Genet. 2016 Dec;33(12):1621-1631.

3. Gautier CA, et al. Mol Neurodegener. 2012 May 25;7:22.

4. Gao F, et al. Aging Cell. 2020 Sep;19(9):e13211.

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