FC131 |CAS:606968-52-9 Probechem Biochemicals

Chemical Structure : FC131

CAS No.: 606968-52-9

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FC131 (FC 131;cyclo(-D-Tyr-Arg-Arg-Nal-Gly-))

货号: PC-61965Not For Human Use, Lab Use Only.

FC131 (cyclo(-D-Tyr-Arg-Arg-Nal-Gly-)) is a selective, cyclopentapeptide CXCR4 antagonist with IC50 of 126 nM, exhibits anti-HIV activity in assays using NL4-3 and IIIB strains with EC50 of 21 nM..

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10 mg	￥2180	In stock
25 mg	￥3880	In stock
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100 mg		Get quote

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生物&药学活性

FC131 (cyclo(-D-Tyr-Arg-Arg-Nal-Gly-)) is a selective, cyclopentapeptide CXCR4 antagonist with IC50 of 126 nM, exhibits anti-HIV activity in assays using NL4-3 and IIIB strains with EC50 of 21 nM.

物理化学性质&存储条件

分子量	729.84
分子式	C36H47N11O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1,1'-(((2S,5S,8S,14R)-14-(4-hydroxybenzyl)-8-(naphthalen-2-ylmethyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecane-2,5-diyl)bis(propane-3,1-diyl))diguanidine

参考文献

1. Tamamura H, et al. J Med Chem. 2005 Jan 27;48(2):380-91.

2. Thiele S, et al. Br J Pharmacol. 2014 Dec;171(23):5313-29.

FC131 (FC 131;cyclo(-D-Tyr-Arg-Arg-Nal-Gly-))

生物&药学活性

物理化学性质&存储条件

参考文献

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FC131 (FC 131;cyclo(-D-Tyr-Arg-Arg-Nal-Gly-))

生物&药学活性

物理化学性质&存储条件

参考文献

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