FAPI-46 (Linofapib bentoxetan)

Chemical Structure : FAPI-46

CAS No.: 2374782-04-2

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货号: PC-27470Not For Human Use, Lab Use Only.

FAPI-46 (Linofapib bentoxetan) is a quinoline-based fibroblast activation protein (FAP)-targeted tracer, FAPI-46 labeled with 68Ga or 177Lu can be used for tumor imaging in a variety of cancers and has higher tumor uptake rates and longer tumor accumulation.

规格	价格	库存
1 mg	￥2480	In stock
2 mg	￥3980	In stock
5 mg	￥5980	In stock
10 mg		Get quote
25 mg		Get quote

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生物&药学活性

FAPI-46 (Linofapib bentoxetan) is a quinoline-based fibroblast activation protein (FAP)-targeted tracer, FAPI-46 labeled with 68Ga or 177Lu can be used for tumor imaging in a variety of cancers and has higher tumor uptake rates and longer tumor accumulation.

物理化学性质&存储条件

分子量	885.97
分子式	C41H57F2N11O9
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]methylamino]propyl]-1-piperazinyl]-2-oxoethyl]-

参考文献

1. Loktev A, et, al. Development of Fibroblast Activation Protein-Targeted Radiotracers with Improved Tumor Retention. J Nucl Med. 2019 Oct;60(10):1421-1429.

2. Moon ES, et, al. EJNMMI Radiopharm Chem. 2020 Jul 29;5(1):19.