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首页-小分子抑制剂&激动剂-Others-Other Targets-F16
F16

Chemical Structure : F16

CAS No.: 36098-33-6

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F16 (F-16;Compound F16)

货号: PC-42131Not For Human Use, Lab Use Only.

A mitochondriotoxic small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines.

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25 mg ￥800 In stock
50 mg ￥1440 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A mitochondriotoxic small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines; inhibits oxidative phosphorylation and inducing mitochondrial transmembrane depolarization, induce apoptosis and necrosis in a variety of tumor cells.

物理化学性质&存储条件

分子量 362.2082
分子式 C16H15IN2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 31 mg/mL
Chemical Name/SMILES

Pyridinium, 4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-, iodide (1:1)

参考文献

1. Fantin VR, et al. Cancer Cell. 2002 Jul;2(1):29-42.

2. Fantin VR, et al. Cancer Res. 2004 Jan 1;64(1):329-36.

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