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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-F059-1017
F059-1017

Chemical Structure : F059-1017

CAS No.:

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F059-1017

货号: PC-24041Not For Human Use, Lab Use Only.

F059-1017 is a potent, selective CDK8 inhibitor with IC50 of 558.1 nM, reduces phosphorylation and expression of signaling mediators associated with inflammation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

F059-1017 is a potent, selective CDK8 inhibitor with IC50 of 558.1 nM, reduces phosphorylation and expression of signaling mediators associated with inflammation.

物理化学性质&存储条件

分子量 339.41
分子式 C19H17NO3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-cyclopentylidene-5-(phenylsulfonyl)indolin-2-one

参考文献

1. Lin TE, et al. Biomed Pharmacother. 2022 Feb;146:112459.

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