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Ezutromid

Chemical Structure : Ezutromid

CAS No.: 945531-77-1

Ezutromid (SMT-C1100;VOX-C1100;BMN-195)

货号: PC-45388Not For Human Use, Lab Use Only.

The first orally bioavailable small molecule utrophin upregulator.

规格 价格 库存 数量
10 mg ¥1200 In stock
50 mg ¥4160 In stock
100 mg ¥7040 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

The first orally bioavailable small molecule utrophin upregulator; demonstrates significant disease modifying effects in DMD models; reduces a number of the pathological effects of dystrophin deficiency, results in reduced pathology, better muscle physiology leading to an increase in overall strength, and an ability to resist fatigue after forced exercise.

Other Indication

Phase 2 Clinical

物理化学性质&存储条件

分子量 337.3923
分子式 C19H15NO3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 10 mg/mL

Chemical Name/SMILES

Benzoxazole, 5-(ethylsulfonyl)-2-(2-naphthalenyl)-

参考文献

1. Tinsley JM, et al. PLoS One. 2011 May 6;6(5):e19189.

2. Tinsley J, et al. J Clin Pharmacol. 2015 Jun;55(6):698-707.

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