Exoticin

Chemical Structure : Exoticin

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货号: PC-22956Not For Human Use, Lab Use Only.

Exoticin is a selective agonist of 6TM μ opioid receptor (6TM-μOR) with Kd of 14 uM, induces 6TM-μOR-dependent signal transduction, shows broad-spectrum analgesic efficacy.

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生物&药学活性

Exoticin is a selective agonist of 6TM μ opioid receptor (6TM-μOR) with Kd of 14 uM, induces 6TM-μOR-dependent signal transduction, shows broad-spectrum analgesic efficacy.
Exoticin shows much weaker affinity for 7TM-μOR.
Exoticin does not activate traditional opioid receptors such as ΜORs, kappa-opioid receptors (KORs), or delta-opioid receptors (DORs).
Slc3a2, Lrrc59, Ppp1cb are endogenous chaperones essential for 6TM-μOR ligand binding and function.

物理化学性质&存储条件

分子量	462.45
分子式	C23H26O10
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,5,6,7,8-Pentamethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one

参考文献

1. Qin F, et al. Phytomedicine. 2024 Jul 26;133:155898.

Exoticin

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物理化学性质&存储条件

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Exoticin

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物理化学性质&存储条件

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