Evixapodlin (GS-4224) | PD-1/PD-L1 inhibitor | Probechem Biochemicals

Chemical Structure : Evixapodlin

CAS No.: 2374856-75-2

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Evixapodlin (GS-4224, GS4224)

货号: PC-38391Not For Human Use, Lab Use Only.

Evixapodlin (GS-4224) is a highly potent, small molecule human PD-1/PD-L1 protein-protein interaction inhibitor with IC50 of 0.213 nM, exhibits potential anticancer and antiviral activities.

规格	价格	库存
5 mg	￥1980	In stock
10 mg	￥2980	In stock
25 mg	￥4880	In stock
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100 mg		Get quote

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生物&药学活性

Evixapodlin (GS-4224) is a highly potent, small molecule human PD-1/PD-L1 protein-protein interaction inhibitor with IC50 of 0.213 nM, exhibits potential anticancer and antiviral activities.

物理化学性质&存储条件

分子量	691.61
分子式	C34H36Cl2N8O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5S,5'S)-5,5'-(((((2,2'-dichloro-[1,1'-biphenyl]-3,3'-diyl)bis(3-methoxypyrazine-5,2-diyl))bis(methylene))bis(azanediyl))bis(methylene))bis(pyrrolidin-2-one)

参考文献

1. Patent WO2019160882A1 (compound number 139).

Evixapodlin (GS-4224, GS4224)

生物&药学活性

物理化学性质&存储条件

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Evixapodlin (GS-4224, GS4224)

生物&药学活性

物理化学性质&存储条件

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