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Etravirine

Chemical Structure : Etravirine

CAS No.: 269055-15-4

Etravirine (R-165335;TMC-125)

货号: PC-46011Not For Human Use, Lab Use Only.

Etravirine (R-165335;TMC-125) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for treatment of HIV-1 infection.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Etravirine (R-165335;TMC-125) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for treatment of HIV-1 infection.

物理化学性质&存储条件

分子量 435.2767
分子式 C20H15BrN6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzonitrile, 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-

参考文献

1. Das K, et al. J Med Chem, 2004, 47(10), 2550-2560.

2. Andries K, et al. Antimicrob Agents Chemother. 2004 Dec;48(12):4680-6.

3. Sankatsing SU, et al. AIDS. 2003 Dec 5;17(18):2623-7.

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