Etomoxir |CAS:124083-20-1 Probechem Biochemicals

Chemical Structure : Etomoxir

CAS No.: 124083-20-1

加入收藏

Etomoxir ((R)-(+)-Etomoxir)

货号: PC-45827Not For Human Use, Lab Use Only.

Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) that inhibits fatty acid β-oxidation in rat liver with IC50 of 5-20 nM.

规格	价格	库存
25 mg	￥1980	In stock
50 mg	￥2980	In stock
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) that inhibits fatty acid β-oxidation in rat liver with IC50 of 5-20 nM.
Etomoxir affects ketogenesis, cholesterol synthesis, and gluconeogenesis both in vitro and in vivo.
Etomoxir decreases viability in LNCaP, VCaP, and patient-derived benign and prostate cancer cells, associated with decreased AR expression, decreased mTOR signaling, and increased caspase-3 activation.
Etomoxir decreases xenograft growth in mice.

物理化学性质&存储条件

分子量	326.8151
分子式	C17H23ClO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, ethyl ester, (2R)-

参考文献

1. Lopaschuk GD, et al. Circ Res. 1988 Dec;63(6):1036-43.

2. Kruszynska YT, et al. Biochem Pharmacol. 1987 Nov 15;36(22):3917-21.

3. Schlaepfer IR, et al. Mol Cancer Ther. 2014 Oct;13(10):2361-71.

Etomoxir ((R)-(+)-Etomoxir)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Etomoxir ((R)-(+)-Etomoxir)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.