Esperamicin A1 | ADC payload | Probechem Biochemicals

Chemical Structure : Esperamicin A1

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Esperamicin A1 (BMY 28175)

货号: PC-70085Not For Human Use, Lab Use Only.

Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin, acts by binding to DNA and causes strand scission, an ADC payload used in development of antibody drug conjugates.

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生物&药学活性

Esperamicin A1 is an enediyne antitumor antibiotics of bacterial origin, acts by binding to DNA and causes strand scission, an ADC payload used in development of antibody drug conjugates.

物理化学性质&存储条件

分子量	1325.54
分子式	C59H80N4O22S4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Carbamic acid, [8-[[4,6-dideoxy-2-O-[2,4-dideoxy-3-O-methyl-4-[(1-methylethyl)amino]-α-L-threo-pentopyranosyl]-4-[[(2,6-dideoxy-4-S-methyl-4-thio-β-D-ribo-hexopyranosyl)oxy]amino]-β-D-glucopyranosyl]oxy]-12-[[2,6-dideoxy-3-O-[4,5-dimethoxy-2-[(2-methoxy-1

参考文献

1. Lam KS, et al. J Antibiot (Tokyo). 1995 Dec;48(12):1497-501.

2. Biggins JB, et al. Science. 2003 Sep 12;301(5639):1537-41.

3. Kumar RA, et al. J Mol Biol. 1997 Jan 17;265(2):173-86.

Esperamicin A1 (BMY 28175)

生物&药学活性

物理化学性质&存储条件

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Esperamicin A1 (BMY 28175)

生物&药学活性

物理化学性质&存储条件

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