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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Vitamin D Receptor (VDR)-Ercalcidiol
Ercalcidiol

Chemical Structure : Ercalcidiol

CAS No.: 21343-40-8

Ercalcidiol (1,25-Dihydroxyvitamin D2;1,25-Dihydroxycalciferol)

货号: PC-45807Not For Human Use, Lab Use Only.

The active circulating metabolite of vitamin D2 that binds to nuclear receptor VDR.

规格 价格 库存 数量
5 mg ¥3288.0 In stock
10 mg ¥4936.0 In stock
25 mg ¥10800 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

The active circulating metabolite of vitamin D2 that binds to nuclear receptor VDR; activates VDR to interact with retinoid X receptor (RXR) and forms the VDR/RXR/cofactor complex, which binds to Vitamin D response elements in the promoter region of target genes to regulate gene transcription.

物理化学性质&存储条件

分子量 412.6478
分子式 C28H44O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Cyclohexanol, 4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexenyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1S,3Z)-

参考文献

1. Nakane M, et al. J Steroid Biochem Mol Biol. 2006 Jan;98(1):72-7.

2. Hollis BW. Nutr Rev. 2007 Aug;65(8 Pt 2):S87-90.

3. Hollis BW, et al. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):473-6.

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