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Erastin

Chemical Structure : Erastin

CAS No.: 571203-78-6

Erastin

货号: PC-22423Not For Human Use, Lab Use Only.

Erastin is a specific ferroptosis-inducing compound, shows RAS-selective lethality, also targetsvoltage-dependent anion channel 3 (VDAC3).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Erastin is a specific ferroptosis-inducing compound, shows RAS-selective lethality, also targetsvoltage-dependent anion channel 3 (VDAC3).

物理化学性质&存储条件

分子量 547.05
分子式 C30H31ClN4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(1-(4-(2-(4-Chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

参考文献

1. Dolma S, et al. Cancer Cell. 2003 Mar;3(3):285-96.

2. Sun X, et al. Oncogene. 2015 Nov 5;34(45):5617-25.

3. Yang WS, et al. Chem Biol. 2008 Mar;15(3):234-45.

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