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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-STAT-Erasin
Erasin

Chemical Structure : Erasin

CAS No.: 2256056-21-8

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Erasin (STAT3 inhibitor Erasin)

货号: PC-61033Not For Human Use, Lab Use Only.

Erasin is a potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays.

规格 价格 库存 数量
5 mg ￥1480 In stock
10 mg ￥2280 In stock
25 mg ￥3680 In stock
50 mg ￥5580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Erasin is a potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays.
Erasin induces apoptosis in Erlotinib-resistant lung cancer cells.

物理化学性质&存储条件

分子量 349.39
分子式 C20H19N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-N'-((6-(tert-butyl)-4-oxo-4H-chromen-3-yl)methylene)nicotinohydrazide

参考文献

1. Lis C, et al. Sci Rep. 2017 Dec 12;7(1):17390.

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