Epothilone A | Tubulin inhibitor | Probechem Biochemicals

Chemical Structure : Epothilone A

CAS No.: 152044-53-6

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Epothilone A (Epo A)

货号: PC-20928Not For Human Use, Lab Use Only.

Epothilone A (Epo A) is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers with Ki of 0.6-1.4 uM.

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10 mg	￥2180	In stock
25 mg	￥3880	In stock
50 mg	￥5880	In stock
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1 g		Get quote

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生物&药学活性

Epothilone A (Epo A) is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers with Ki of 0.6-1.4 uM.
Epothilone A (Epo A) shows highly cytotoxic effect (IC50=0.05 μM) in vitro of human T-24 bladder carcinoma cell line.

物理化学性质&存储条件

分子量	493.66
分子式	C26H39NO6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(C[C@H](O)C1(C)C)O[C@H](/C(C)=C/C2=CSC(C)=N2)C[C@]3([H])O[C@]3([H])CCC[C@H](C)[C@H](O)[C@@H](C)C1=O

参考文献

1. Kowalski RJ, et al. J Biol Chem. 1997 Jan 24;272(4):2534-41.

Epothilone A (Epo A)

生物&药学活性

物理化学性质&存储条件

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Epothilone A (Epo A)

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