Epolactaene |Topo II inhibitor Probechem Biochemicals

Chemical Structure : Epolactaene

加入收藏

Epolactaene

货号: PC-61905Not For Human Use, Lab Use Only.

Epolactaene is a neuritogenic fungal isolate that arrests the cell cycle at the G0/G1 phase and induces the outgrowth of neurites in human neuroblastoma SH-SY5Y cells.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Epolactaene is a neuritogenic fungal isolate that arrests the cell cycle at the G0/G1 phase and induces the outgrowth of neurites in human neuroblastoma SH-SY5Y cells.
Epolactaene inhibits DNA topoisomerase II (topo II), binds to Hsp60 Cys442 resulting in the inhibition of chaperone activity.
Epolactaene also reacts with N-acetylcysteine methyl ester and induces the disulfide formation.

物理化学性质&存储条件

分子量	389.45
分子式	C21H27NO6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl (2E,3E,5E,9E)-2-ethylidene-11-[(1R,5R)-4-hydroxy-4-methyl-2-oxo-6-oxa-3-azabicyclo[3.1.0]hexan-1-yl]-4,10-dimethyl-11-oxoundeca-3,5,9-trienoate

参考文献

1. Kakeya H, et al. J Antibiot (Tokyo). 1995 Jul;48(7):733-5.

2. Nagumo Y, Bioorg Med Chem Lett. 2004 Sep 6;14(17):4425-9.

3. Nagumo Y, et al. Biochem J. 2005 May 1;387(Pt 3):835-40.

Epolactaene

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Epolactaene

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.