EpoY (SD-142)

Chemical Structure : EpoY

CAS No.: 245660-13-3

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货号: PC-28343Not For Human Use, Lab Use Only.

EpoY (SD-142) is an irreversible inhibitor of brain's primary tubulin tyrosine carboxypeptidase (TCP) with IC50 of 500 nM, a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP), effectively decreases levels of detyrosinated alpha-tubulin, which is crucial for microtubule dynamics and neuronal differentiation.

规格	价格	库存
5 mg	￥2180	In stock
10 mg	￥3580	In stock
25 mg	￥5580	In stock
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100 mg		Get quote

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生物&药学活性

EpoY (SD-142) is an irreversible inhibitor of brain's primary tubulin tyrosine carboxypeptidase (TCP) with IC50 of 500 nM, a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP), effectively decreases levels of detyrosinated alpha-tubulin, which is crucial for microtubule dynamics and neuronal differentiation.

物理化学性质&存储条件

分子量	323.30
分子式	C15H17NO7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((2S,3S)-3-(Ethoxycarbonyl)oxirane-2-carbonyl)-L-tyrosine

参考文献

1. Aillaud C, et al. Science. 2017 Dec 15;358(6369):1448-1453.

2. Eaton DM, et al. Sci Transl Med. 2024 Jul 17;16(756):eadm8842.

EpoY (SD-142)

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物理化学性质&存储条件

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EpoY (SD-142)

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