Epalrestat | Aldose reductase inhibitor | Probechem Biochemicals

Chemical Structure : Epalrestat

CAS No.: 82159-09-9

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Epalrestat (ONO-2235, ONO2235)

货号: PC-45922Not For Human Use, Lab Use Only.

Epalrestat (ONO-2235) is a noncompetitive and reversible aldose reductase inhibitor with IC50 of 10 nM and 26 nM for purified aldose reductase from rat lens and human placenta, respectively.

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25 mg	￥780	In stock
50 mg	￥1180	In stock
100 mg	￥1780	In stock
250 mg		Get quote

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生物&药学活性

Epalrestat (ONO-2235) is a noncompetitive and reversible aldose reductase inhibitor with IC50 of 10 nM and 26 nM for purified aldose reductase from rat lens and human placenta, respectively.
Epalrestat (ONO-2235) is used for the treatment of diabetic neuropathy.

物理化学性质&存储条件

分子量	319.3986
分子式	C15H13NO3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 3.1 mg/mL
Chemical Name/SMILES	3-Thiazolidineacetic acid, 5-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-, (5Z)-

参考文献

1. Yasuda H, et al. Diabetes. 1989 Jul;38(7):832-8.

2. Terashima H, et al. J Pharmacol Exp Ther. 1984 Apr;229(1):226-30.

3. Hotta N, et al. Diabet Med. 2012 Dec;29(12):1529-33.

Epalrestat (ONO-2235, ONO2235)

生物&药学活性

物理化学性质&存储条件

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Epalrestat (ONO-2235, ONO2235)

生物&药学活性

物理化学性质&存储条件

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