Englerin A

Chemical Structure : Englerin A

CAS No.: 1094250-15-3

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货号: PC-23880Not For Human Use, Lab Use Only.

Englerin A is a selective inhibitor of renal cancer cell growth with GI50 of 1-87 nM, also is a potent agonist of TRPC ion channels containing TRPC4 and TRPC5 subunits.

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1 mg	￥3280	In stock
2 mg	￥5280	In stock
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生物&药学活性

Englerin A is a selective inhibitor of renal cancer cell growth with GI50 of 1-87 nM, also is a potent agonist of TRPC ion channels containing TRPC4 and TRPC5 subunits.

物理化学性质&存储条件

分子量	442.55
分子式	C26H34O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,3aR,4S,5R,7R,8S,8aR)-5-(2-Hydroxyacetoxy)-7-isopropyl-1,4-dimethyldecahydro-4,7-epoxyazulen-8-yl cinnamate

参考文献

1. Ratnayake R, et al. Org Lett. 2009 Jan 1;11(1):57-60.

2. Wardas B, et al. Mol Pharmacol. 2023 Oct;104(4):144-153.

3. Seenadera SPD, et al. ACS Med Chem Lett. 2022 Aug 22;13(9):1472-1476.

Englerin A

生物&药学活性

物理化学性质&存储条件

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Englerin A

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