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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Estrogen Receptor/ERR-Endoxifen hydrochloride
Endoxifen hydrochloride

Chemical Structure : Endoxifen hydrochloride

CAS No.: 1197194-41-4

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Endoxifen hydrochloride

货号: PC-45541Not For Human Use, Lab Use Only.

A metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A metabolite of tamoxifen, orally active non-steroidal selective estrogen receptor modulator (SERM) for the treatment of estrogen receptor-positive breast cancer.

Breast Cancer

Phase 1 Clinical

物理化学性质&存储条件

分子量 409.9483
分子式 C25H28ClNO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 35 mg/mL
Chemical Name/SMILES

Phenol, 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-, hydrochloride (1:1)

参考文献

1. Brauch H, et al. Clin Chem. 2009 Oct;55(10):1770-82.

2. Markopoulos C, et al. World J Clin Oncol. 2014 Aug 10;5(3):374-81.

3. Mugundu GM, et al. Drug Metab Dispos. 2012 Feb;40(2):389-96.

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