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首页-小分子抑制剂&激动剂-Others-Other Targets-Endosidin 2
Endosidin 2

Chemical Structure : Endosidin 2

CAS No.: 1839524-44-5

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Endosidin 2 (ES-2, Endosidin2)

货号: PC-70315Not For Human Use, Lab Use Only.

Endosidin 2 (Endosidin2, ES2) is a small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.

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10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Endosidin 2 (Endosidin2, ES2) is a small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.

物理化学性质&存储条件

分子量 414.17
分子式 C15H12FIN2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-3-fluoro-N'-(4-hydroxy-3-iodo-5-methoxybenzylidene)benzohydrazide

参考文献

1. Zhang C, et al. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E41-50.

2. Drakakaki G, et al. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17850-5.

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