Empagliflozin | SGLT2 inhibitor | Probechem Biochemicals

Chemical Structure : Empagliflozin

CAS No.: 864070-44-0

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Empagliflozin (BI-10773, BI 10773)

货号: PC-22576Not For Human Use, Lab Use Only.

Empagliflozin (BI-10773) is a potent, selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with IC50 of 3.1 nM (hSGLT-2), has a high degree of selectivity over SGLT-1, 4, 5 and 6, has potential for the oral treatment of type 2 diabetes mellitus (T2DM).

规格	价格	库存
50 mg	￥780	In stock
100 mg	￥980	In stock
500 mg	￥1680	In stock
1 g		Get quote

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生物&药学活性

Empagliflozin (BI-10773) is a potent, selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with IC50 of 3.1 nM (hSGLT-2). has a high degree of selectivity over SGLT-1, 4, 5 and 6, has potential for the oral treatment of type 2 diabetes mellitus (T2DM).

物理化学性质&存储条件

分子量	450.91
分子式	C23H27ClO7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

参考文献

1. Aires I, et al. Curr Opin Investig Drugs. 2010 Oct;11(10):1182-90.

2. Grempler R, et al. Diabetes Obes Metab. 2012 Jan;14(1):83-90.

Empagliflozin (BI-10773, BI 10773)

生物&药学活性

物理化学性质&存储条件

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Empagliflozin (BI-10773, BI 10773)

生物&药学活性

物理化学性质&存储条件

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