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首页-小分子抑制剂&激动剂-GPCR-P2Y Receptor-Elinogrel
Elinogrel

Chemical Structure : Elinogrel

CAS No.: 936500-94-6

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Elinogrel (PRT-060128, PRT060128)

货号: PC-61587Not For Human Use, Lab Use Only.

Elinogrel (PRT060128) is a selective, reversible, competitive and direct-acting P2Y12 receptor antagonist with IC50 of 20 nM.

规格 价格 库存 数量
5 mg ￥1180 In stock
10 mg ￥1880 In stock
25 mg ￥2980 In stock
50 mg ￥4980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Elinogrel (PRT060128) is a selective, reversible, competitive and direct-acting P2Y12 receptor antagonist with IC50 of 20 nM.
Elinogrel (PRT060128) shows potent antiplatelet effects for the treatment of acute coronary syndrome and prevention of secondary thrombotic events.

物理化学性质&存储条件

分子量 523.945
分子式 C20H15ClFN5O5S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[4-(6-Fluoro-7-methylamino-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)phenyl]-N'-[(5-chlorothiophen-2-yl)sulfonyl]urea

参考文献

1. Siller-Matula JM, et al. Br J Pharmacol. 2010 Feb 1;159(3):502-17.

2. Leonardi S, et al. Am Heart J. 2010 Jul;160(1):65-72.

3. Oestreich JH. Curr Opin Investig Drugs. 2010 Mar;11(3):340-8.

4. André P, et al. J Pharmacol Exp Ther. 2011 Jul;338(1):22-30.

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