Chemical Structure : Elamipretide acetate
CAS No.: 1334953-95-5
货号: PC-27242Not For Human Use, Lab Use Only.
Elamipretide acetate (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥1580 | In stock | |
| 10 mg | ¥2480 | In stock | |
| 25 mg | ¥4280 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Elamipretide acetate (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.
Elamipretide prevents mitochondrial depolarization, reduces islet cell apoptosis, increases islet cell yield, and improves posttransplantation function.
| 分子量 | 699.85 | |
| 分子式 | C34H53N9O7 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-6-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide acetate |
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1. Thomas DA, et al. J Am Soc Nephrol. 2007 Jan;18(1):213-22.
2. Zhao K, et al. Biochem Pharmacol. 2005 Dec 5;70(12):1796-806.
3. Mizuguchi Y, et al. Am J Physiol Renal Physiol. 2008 Nov;295(5):F1545-53.
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