Elacestrant (RAD-1901) | SERD | Probechem Biochemicals

Chemical Structure : Elacestrant

CAS No.: 722533-56-4

加入收藏

Elacestrant (RAD-1901, RAD1901)

货号: PC-45733Not For Human Use, Lab Use Only.

Elacestrant (RAD-1901) is a novel, orally bioavailable small-molecule selective estrogen receptor degrader (SERD).

规格	价格	库存
5 mg	￥1880	In stock
10 mg	￥2980	In stock
25 mg	￥4780	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Elacestrant (RAD-1901) is a novel, orally bioavailable small-molecule selective estrogen receptor degrader (SERD).
Elacestrant (RAD-1901) inhibits ERα expression in MCF-7 cells (IC50=0.6 nM).
Elacestrant (RAD-1901) induces the degradation of ER, inhibits ER-mediated signaling and growth of ER+ breast cancer cell lines in vitro and in vivo, and significantly inhibits tumor growth of multiple PDX models.

物理化学性质&存储条件

分子量	458.6349
分子式	C30H38N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6R)-

参考文献

1. Wardell SE, et al. Endocr Relat Cancer. 2015 Oct;22(5):713-24.

2. Garner F, et al. Anticancer Drugs. 2015 Oct;26(9):948-56.

3. Bihani T, et al. Clin Cancer Res. 2017 May 4. pii: clincanres.2561.2016.

Elacestrant (RAD-1901, RAD1901)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Elacestrant (RAD-1901, RAD1901)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.