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Eclitasertib

Chemical Structure : Eclitasertib

CAS No.: 2125450-76-0

Eclitasertib (DNL-758, SAR-443122, DNL758, SAR443122)

货号: PC-72533Not For Human Use, Lab Use Only.

Eclitasertib (DNL-758, SAR-443122) is a potent, orally bioavailable, small-molecule RIPK1 inhibitor with IC50 of <1 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Eclitasertib (DNL-758, SAR-443122) is a potent, orally bioavailable, small-molecule RIPK1 inhibitor with IC50 of <1 uM.

物理化学性质&存储条件

分子量 378.39
分子式 C19H18N6O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydropyrido[3,2-b][1,4]oxazepin-3-yl)-4H-1,2,4-triazole-3-carboxamide

参考文献

1. WO2017136727A2, Example 42.

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