EX-229 |CAS:1219739-36-2 Probechem Biochemicals

Chemical Structure : EX-229

CAS No.: 1219739-36-2

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EX-229 (EX 229;EX229)

货号: PC-60179Not For Human Use, Lab Use Only.

EX-229 is a small molecule AMPK activator that dose-dependently increases AMPK activity of α1-, α2-, β1- and β2-containing complexes at 50 uM.

规格	价格	库存
10 mg	￥980	In stock
25 mg	￥1680	In stock
50 mg	￥2680	In stock
100 mg		Get quote

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生物&药学活性

EX-229 is a small molecule AMPK activator that dose-dependently increases AMPK activity of α1-, α2-, β1- and β2-containing complexes at 50 uM.
EX-229 induces AMPK activation and glucose uptak in a wortmannin-independent manner; increases fatty acid oxidation in L6 myotubes.

物理化学性质&存储条件

分子量	431.876
分子式	C24H18ClN3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-{[6-chloro-5-(1-methylindol-5-yl)-1H-benzimidazol-2-yl]oxy}-2-methyl-benzoic acid

参考文献

1. Lai YC, et al. Biochem J. 2014 Jun 15;460(3):363-75.

2. Bultot L, et al. Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E706-E719.

3. Patent WO2010036613, EX229.

EX-229 (EX 229;EX229)

生物&药学活性

物理化学性质&存储条件

参考文献

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EX-229 (EX 229;EX229)

生物&药学活性

物理化学性质&存储条件

参考文献

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