EU1622-240

Chemical Structure : EU1622-240

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货号: PC-23269Not For Human Use, Lab Use Only.

EU1622-240 is a positive allosteric modulator of NMDA receptors (NMDARs), enhances current response to saturating agonist (doubling response amplitude at 0.2-0.5 µM).

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EU1622-240 is a positive allosteric modulator of NMDA receptors (NMDARs), enhances current response to saturating agonist (doubling response amplitude at 0.2-0.5 µM).
EU1622-240-bound NMDARs channels activated by a single agonist (glutamate or glycine) open to a unique conductance level with different pore properties and Mg2+ sensitivity, in contrast to channels arising from activation of NMDARs with both co-agonists bound.

物理化学性质&存储条件

分子量	478.31
分子式	C20H14BrF2N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(3-bromo-4-fluorophenyl)-6-ethynyl-3-(2-(3-fluoro-3-methylazetidin-1-yl)-2-oxoethyl)thieno[2,3-d]pyrimidin-4(3H)-one

参考文献

1. Elijah Z Ullman, et al. Mol Pharmacol. 2024 Oct 23:MOLPHARM-AR-2024-001019.

EU1622-240

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物理化学性质&存储条件

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EU1622-240

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物理化学性质&存储条件

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