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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-EPZ033294
EPZ033294

Chemical Structure : EPZ033294

CAS No.: 1887195-17-6

EPZ033294 (EPZ 033294)

货号: PC-21040Not For Human Use, Lab Use Only.

EPZ033294 is a potent, selective inhibitor of SMYD2 with biochemical IC50 of 3.9 nM, and function of cellular methylation IC50 of 29 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

EPZ033294 is a potent, selective inhibitor of SMYD2 with biochemical IC50 of 3.9 nM, and function of cellular methylation IC50 of 29 nM.

物理化学性质&存储条件

分子量 411.89
分子式 C20H22ClN7O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(C1=CN(C2CC2)N=N1)NC3CN(CC4=CN(CC5=CC=C(Cl)C=C5)N=C4)C3

参考文献

1. Michael J Thomenius, et al. PLoS One. 2018 Jun 1;13(6):e0197372.

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