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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-EPZ 025654
EPZ 025654

Chemical Structure : EPZ 025654

CAS No.: 1888328-89-9

EPZ 025654 (EPZ025654, EPZ-025654, GSK 35336023)

货号: PC-61209Not For Human Use, Lab Use Only.

EPZ025654 (GSK 35336023) is a potent, selective arginine methyltransferase CARM1 inhibitor with IC50 of 3 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    EPZ025654 (GSK 35336023) is a potent, selective arginine methyltransferase CARM1 inhibitor with IC50 of 3 nM.

    物理化学性质&存储条件

    分子量 577.086
    分子式 C29H33ClN8O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-1-(3-(4-(2-(azetidin-1-yl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)-6-(3,5-dimethylisoxazol-4-yl)-5-methylpyrimidin-2-yl)-4-chlorophenoxy)-3-(methylamino)propan-2-ol

    参考文献

    1. Drew AE, et al. Sci Rep. 2017 Dec 21;7(1):17993.

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