ENMD-2076 |CAS:934353-76-1 Probechem Biochemicals

Chemical Structure : ENMD-2076

CAS No.: 934353-76-1

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ENMD-2076 (ENMD 2076;ENMD2076)

货号: PC-42766Not For Human Use, Lab Use Only.

ENMD-2076 is a multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2, respectively.

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10 mg	￥880	In stock
25 mg	￥1380	In stock
50 mg	￥2180	In stock
100 mg		Get quote

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生物&药学活性

ENMD-2076 is a multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2, respectively.
ENMD-2076 also inhibits Aurora B, c-Kit, FGFR1 (IC50=100-350 nM).
ENMD-2076 is orally bioactive.

物理化学性质&存储条件

分子量	375.4701
分子式	C21H25N7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Pyrimidinamine, 6-(4-methyl-1-piperazinyl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(1E)-2-phenylethenyl]-

参考文献

1. Tentler JJ, et al. Clin Cancer Res. 2010 Jun 1;16(11):2989-98.

2. Matulonis UA, et al. Eur J Cancer. 2013 Jan;49(1):121-31.

3. Fletcher GC, et al. Mol Cancer Ther. 2011 Jan;10(1):126-37.

ENMD-2076 (ENMD 2076;ENMD2076)

生物&药学活性

物理化学性质&存储条件

参考文献

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ENMD-2076 (ENMD 2076;ENMD2076)

生物&药学活性

物理化学性质&存储条件

参考文献

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