Chemical Structure : EML734
货号: PC-21012Not For Human Use, Lab Use Only.
EML734 is a selective small molecule inhibitor of protein arginine methyltransferase isoforms, PRMT7 and PRMT9 with IC50 of 0.32 and 0.89 uM, respectively.
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EML734 is a selective small molecule inhibitor of protein arginine methyltransferase isoforms, PRMT7 and PRMT9 with IC50 of 0.32 and 0.89 uM, respectively.
EML734 dispaly little to no activity against other PRMTs.
EML734 affects PRMT activity even in a cellular context.
分子量 | 608.62 | |
分子式 | C27H32N10O7 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Alessandra Feoli, et al. J Med Chem. 2023 Aug 10. doi: 10.1021/acs.jmedchem.3c01030.
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