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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-EML405
EML405

Chemical Structure : EML405

CAS No.: 2101954-79-2

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EML405 (EML-405, EML 405)

货号: PC-70162Not For Human Use, Lab Use Only.

EML405 (EML 405) is a small-molecule inhibitor of the methyl-lysine reader protein Spindlin1 (SPIN1) with Kd of 14 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    EML405 (EML 405) is a small-molecule inhibitor of the methyl-lysine reader protein Spindlin1 (SPIN1) with Kd of 14 uM.
    EML405 shows novel interaction with the Tudor-domain-containing protein Spindlin1 (SPIN1).

    物理化学性质&存储条件

    分子量 585.837
    分子式 C36H51N5O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (2-(phenylamino)-1,4-phenylene)bis((4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)methanone)

    参考文献

    1. Bae N, et al. Nat Chem Biol. 2017 May 15. doi: 10.1038/nchembio.2377.

    2. Wang W, et al. EMBO Rep. 2011 Oct 28;12(11):1160-6.

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