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首页-小分子抑制剂&激动剂-Others-Other Targets-ELOVL1-IN-2
ELOVL1-IN-2

Chemical Structure : ELOVL1-IN-2

CAS No.: 2761063-79-8

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ELOVL1-IN-2

货号: PC-26755Not For Human Use, Lab Use Only.

ELOVL1-IN-2 is a specific ELOVL1 inhibitor with IC50 of 21 μM, inhibits the condensation step of fatty acid elongation and reduces the synthesis of very long-chain fatty acids, including C26:0 VLCFA.

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50 mg ￥1280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ELOVL1-IN-2 is a specific ELOVL1 inhibitor with IC50 of 21 μM, inhibits the condensation step of fatty acid elongation and reduces the synthesis of very long-chain fatty acids, including C26:0 VLCFA.

物理化学性质&存储条件

分子量 294.33
分子式 C18H15FN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-(4-fluorophenethoxy)-3,3'-bipyridine

参考文献

1. Boyd MJ, et al. Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1. J Med Chem. 2021;64(24):17777-17794.

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